Denture Adhesives Side Effects, Benefits & Common Problems
Last Updated on March 25, 2025 by Jade Roberts
Fact Checked by Dr. M. Mansoor Majeed
Dr. M. Mansoor Majeed (BDS, MDS, CHPE) has over ten years of experience as a practicing dentist, medical writer, and researcher. He also works as an assistant professor at a renowned health sciences university. Dr. Mansoor has written more than 30 research articles, which have been published in renowned medical journals, and has presented his research at conferences worldwide.
Denture adhesives are a good solution for denture wearers to hold dentures in place. However, potential issues can develop.
In this article we’ll look at what denture adhesives are, how they work, discuss some denture adhesives side effects, other problems you may experience, and how to fix issues you may have.
What Are Denture Adhesives?
Denture adhesives are used as denture glue to hold dentures firmly in place in your mouth. These adhesives are available in three common formats: paste, powder, and pad.
When you use a dental adhesive, you apply it directly to the fitting surface of the full denture plate or the base. When you put the denture in your mouth, the adhesive sits between the plate and your gums.
The adhesive is meant for daily use. So before going to bed each night, it’s important to make sure that you carefully remove the denture adhesive from the denture plates as well as your gums or oral tissues when you clean your dentures.
The Benefits of Denture Adhesive
There are a few basic advantages to using a denture adhesive cream on dentures. They include:
- Prevent Your Dentures From Moving: As you age, you might not find your dentures fitting as well as they used to because your gums change shape over time. However, using a denture adhesive ensures the firm positioning of the dentures in your mouth.
- Improved Comfort: As for comfort, you have to consider that a denture is a hard material that is going to spend most of the day on the soft tissue of your mouth. The dental adhesive makes that fit a lot more comfortable for the wearer.
- Improves Your Self-Confidence: Since your dentures will be firmly held in place, you don’t have to worry about your dentures moving inside your mouth (or falling out) when you are around others when talking, and eating. This will help with your self-confidence, especially when in public, immensely.
6 Common Problems With Denture Adhesives
The biggest issue that can result from the use of denture adhesives is what would be classified as side effects. Here are the top six denture adhesive side effects to be aware of:
- Bone Loss: Denture wearers are subject to the natural loss of bone density. This happens over time as your jawbone no longer receives the type of stimulation it once experienced with teeth or dental implants in place. As the bone deteriorates, there is less of it to support the denture plates. One thing that can speed up bone loss is the habit of wearing dentures that do not fit properly. Some people may be over-reliant on denture adhesives to keep their dentures in place rather than getting new dentures or a denture reline when their dentures don’t fit properly. This is why it is vital for regular denture fixing or repair to ensure a snug, comfortable fit.
- Zinc Toxicity: Zinc is a requirement of the human body but only in small amounts. It is used to assist with proper healing and good immune function. However, if zinc enters the body in large amounts, it can be toxic, causing nerve damage and prolonged numbness. Denture adhesives were loaded with zinc, and many manufacturers have created new formulas that are zinc-free and better for denture wearers. Read the labels to ensure you are using a zinc-free denture adhesive product.
- Stomach Problems: The complex mixture of chemical compounds used in the ingredients of any denture glue can be dangerous to your digestive system if swallowed. The packaging of these products has warnings listed to this effect. One way to ensure you do not swallow the adhesive product is to apply only enough that extra glue does not ooze out from the sides of your dentures and into your mouth. Once you find the correct amount to apply, you can minimize the possibility of this being an issue.
- Allergic Reaction: As mentioned above, the formula used in creating any kind of denture adhesive is a mixture of many different chemical compounds. This is true even with the best denture adhesive on the market. Therefore, it’s possible that there could be an ingredient that may trigger an allergic reaction of some kind. This would make wearing dentures even more difficult if that reaction affected the gums or mouth. Be sure to read the ingredient list before trying a dental glue product.
- Bad Taste: Considering that zinc and other chemicals are used in dental glue, it only makes sense that it is not going to taste very good. For some denture wearers, the taste of the denture cream is enough to make them sick to their stomachs. With this kind of reaction, it becomes difficult to use a product that ends up so close to the taste buds. However, over time, many denture wearers can get used to the taste or smell of the products, and they no longer react to them.
- Denture Movement: Denture adhesives may lose their hold over time, causing the dentures to slip, shift, or move around in the mouth. This can cause discomfort, soreness, or pain.
Denture Adhesives Side Effects FAQs
Are there side effects when using denture adhesives?
Typically, any side effects that develop through the use of denture adhesives are not normally considered harmful. However, it is not uncommon for some individuals to be triggered by ingredients found in denture adhesives. These triggers can result in allergic reactions. Denture adhesives containing acrylic acid or zinc are usually the culprits.
Some people can have serious reactions to acrylic acid in denture adhesives. Symptoms include face or tongue swelling, breathing problems, or anaphylaxis. Seek emergency medical attention immediately.
If your denture adhesive contains zinc, then zinc toxicity might result from prolonged use. Be conscious of signs such as arm or leg weakness, body tingles, or numbness.
Contact your dental professional if denture adhesives cause you any side effects.
What should I do if I experience a side effect from my denture adhesive?
There are two key actions to take if you experience side effects from using denture adhesives. First, stop using the product. Second, contact your dental professional.
Side effects may go away as soon as you stop using the dental adhesive. Your dental professional may suggest a change in products that could eliminate the side effects. Or, they may suggest adjustments to your dentures to improve how they fit in your mouth. This may mean that you don’t require the use of denture adhesives. Or, if these courses of action don’t help, other treatments may be necessary.
Can using too much denture adhesive cause side effects?
When too much denture adhesive is used, it can leak out from between your gums and dentures. This leaking can cause the adhesive to come into contact with the tissues in your mouth. This may irritate and make your mouth sore or inflamed. Also, when too much denture adhesive is used, it can impact how dentures fit. This can cause them to slip out of place.
If there is excess dental adhesive in your mouth, you could swallow some. Ingesting denture adhesive can cause nausea, diarrhea, or vomiting.
If denture adhesives trigger any reaction, consult with your dental professional. They can identify the cause and provide appropriate treatment.
Should I stop using my denture adhesive if I experience side effects?
If your denture adhesive causes a side effect, stop using it immediately. Contact your dental professional for advice. It may require changing denture adhesive products or having adjustments performed on your dentures.
Can denture adhesive side effects be prevented?
Preventing all side effects may not be possible. However, the risk of experiencing issues can be reduced by:
– Following the Instructions: You will find instructions printed on the denture adhesive packaging. Read and follow them.
– Using the Recommended Amount: The instructions will tell you what the recommended amount of denture adhesive should be. Use only this amount to hold your dentures in place.
– Keeping Your Dentures Clean: Before you apply denture adhesive, ensure that the denture is cleaned properly. Failing to do this may cause gum irritation should food particles or bacteria get trapped between gums and dentures.
– Avoiding Use If Gums Are Damaged or Inflamed: If you are experiencing pain in your gums because they are swollen or irritated, refrain from applying denture adhesive. Allow your gums to heal before using denture adhesive again.
– Avoiding Allergens: Read the ingredient list on the packaging. If you’re allergic to any ingredient, don’t use the denture adhesive.
Final Thoughts
While denture adhesives are great for holding dentures in place, they aren’t always the best solution. Your dental professional may advise adjusting your dentures if your dentures are loose fitting.
Using too much can cause your dentures to slip and can result in irritation to your gums. Plus, excess denture adhesive may be swallowed, which can cause other health issues. There are ingredients contained in denture adhesives that may result in allergic reactions. To avoid this, read the list of ingredients, and if you have a known allergy to any, change products.
Remember, if you have a reaction from using denture adhesive, stop using it. Seek medical attention if the reaction is serious. Otherwise, consult with your dental professional to determine the possible cause and appropriate treatment.
I am allergic to Iodine …..Is there Iodine in denture adhesive ?
Hi Nadine, and thanks for your question.
I am not aware of iodine in denture adhesive. However, you may wish to check out the ingredient list on the packaging, or via the manufacturer’s website.
Eg. See Fixodent ingredients – click here.
By swallowing the teeth adhesive can this cause problems with constipation in a person ?
Hello Savinia
I have not experienced issues like this. But please note, I am not a healthcare professional so if you have any specific questions, you may want to see a professional.
From the research that I have done, swallowing a small amount of denture adhesive is unlikely to cause significant problems with constipation. Denture adhesive is typically formulated to be safe if accidentally ingested in small quantities.
However, if you have accidentally swallowed teeth adhesive and are experiencing symptoms such as constipation, it’s a good idea to consult a medical professional for guidance. While the adhesive itself might not directly cause constipation, there could be other factors involved that are leading to your symptoms. It’s always best to seek medical advice to ensure your health and well-being.
I use a dental adhesive and I am also suffering from dangerous uric acid readings which are causing joint pain and some bleeding gums
Could this be caused by my dental adhesive.?Uric acid reading are dangerous as I have said over 9 when my understanding is that they should be 5.
At the moment, the “medical professionals” are treating me with gout medications like Allopurinol, even though I do not have gout.
Hello Stanley
Thank you for your question, and I am sorry to hear of the issues you are having.
Please note that I am not a dentist or health professional, so any comments are from my personal experience or research that I have done.
Most of the time denture adhesives are pretty safe, but bodies can react differently. If you’re thinking your adhesive might be causing an issue, it’s a good idea to chat with your dentist about it. High uric acid can be a real pain, literally. From what I understand it might lead to gout. That’s something you’d want to manage with a doctor’s help. They can guide you on how to keep it under control. Bleeding gums are a bit of a concern. It could be something like gum disease. It may not be directly linked to the uric acid issue, but it’s still worth mentioning to your dentist.
With everything going on – the joint pain, high uric acid, and gum issues – it’s really important to have a chat with both your doctor and dentist. They should be able to work together to figure out what’s going on and how to make you feel better.
Best of luck with it, and let us know how you go.
Could these products cause a cough?
Hello Ell
Thanks for your question. While a cough isn’t a commonly reported side effect of denture adhesives, it’s not impossible — especially if you’re sensitive or allergic to one of the ingredients.
Some adhesives can cause irritation or an allergic reaction in the mouth or throat, particularly if excess adhesive leaks out and is accidentally swallowed or comes into contact with soft tissues. In rare cases, this irritation might trigger a cough or throat discomfort.
If you’ve recently started using a new adhesive and noticed a persistent cough, it’s a good idea to stop using the product and see if the symptoms improve. Also, check the ingredient list — some people may react to compounds like zinc or certain preservatives.
To be safe, consult with your dentist or doctor to rule out any other underlying causes. They can help you identify if the adhesive is contributing to the issue and suggest an alternative product if needed.
Can denture adhesives make one thirsty?
Hello Nan
Denture adhesives themselves usually don’t directly cause thirst. However, they can sometimes contribute to a dry feeling in your mouth, which can make you feel more thirsty than normal. Here’s why:
– Some adhesives can slightly reduce saliva flow where they’re applied.
– If a denture adhesive leaves a bad taste (which some users report), it might encourage you to drink more water to get rid of it.
– Wearing dentures in general can sometimes lead to dry mouth, especially if you already have other factors like certain medications, mouth breathing, or smoking.
If you find that you are feeling very dry or thirsty after using a denture adhesive, it’s a good idea to:
– Drink more water throughout the day.
– Use sugar-free gum or candy to help stimulate saliva.
– Check with your dentist about trying a different adhesive that might be more comfortable for you.
If dry mouth continues, mention it to your dentist because they can help find the cause and suggest ways to ease it.
Hope that helps.
Why have an ingredient based on petroleum in the adhesive.
Hi Pete,
That’s a great question. Some denture adhesives contain ingredients derived from petroleum because they help create a strong, lasting seal and improve the texture of the adhesive. However, understandably not everyone is comfortable with petroleum-based ingredients, and there are now more alternatives available, including zinc-free and more natural formulations.
If you’re concerned, it’s worth looking for adhesives that clearly state they are free from petroleum-based ingredients. Always feel free to check with your dentist too, as they can help recommend an option that best suits your needs.
Thanks for your comment!
I have been using denture adhesive for years and have since experienced numbness in my fingers, burping a lot
And diarrhoea and did not know until I came across this now!!! I will stop using and get zinc free adhesive!! Gosh all this time I thought I was lacking Vitamins and been taking as such!!! Glad I came across this!
Hi Florie,
I’m so glad you found this article helpful! It sounds like you’ve been experiencing some of the common side effects associated with adhesives containing zinc. Switching to a zinc-free denture adhesive is definitely a smart move. However, it’s also important that you speak with your doctor or dentist about the symptoms you’ve mentioned, especially the numbness, to ensure everything is checked thoroughly.
Thanks for sharing your experience, as it may help others become more aware too! If you have any more questions, just let us know — we’re here to help.
Take care!
I have lost my sense of taste. Sometimes I can taste some things… sometimes I can’t… But all the time, any taste I have is not what I’m eating. Everyone is telling me it’s because I had Covid. This started weeks after I had Covid, but during the time I had a lot of dental work done. I was given a temporary partial to wear and was given Fixodent which I’ve been using for probably one year. Not sure of dates. My dentist gave me Polygrip to use, however, his staff gave me Fixodent which worked great, so I didn’t go with Polygrip. Now I’m wondering if this loss of taste, which is getting worse, can be from Fixodent and can Polygrip also effect ones taste. I appreciate your help… This has been very frustrating.
Hello Barbara,
Thank you for reaching out and sharing your experience — I understand how frustrating and concerning losing your sense of taste can be.
Taste changes or loss of taste can indeed happen for several reasons, including dental work, use of denture adhesives, or after-effects of illnesses such as COVID-19. While COVID-related taste issues are common, denture adhesives, particularly those containing zinc, can occasionally impact taste as well.
Fixodent and Polygrip both offer zinc-free versions specifically designed to reduce taste interference and minimize potential side effects. You may find it beneficial to switch to a zinc-free adhesive (such as zinc-free Polygrip) for a while to see if your taste improves. Also, make sure to use adhesives sparingly, applying only what’s necessary to keep your dentures secure, as excessive use can contribute to side effects.
Given your symptoms and timing, it’s important to discuss this issue directly with your dentist or healthcare provider. They might recommend temporarily stopping or switching adhesives to pinpoint the exact cause.
I hope this information helps you find relief soon. Feel free to reach out if you have more questions — we’re here to support you.
Let us know how you get on. All the best.
What is the problem with dental adhesives for people who have problems with swallowing or choking? I had whooping cough at 14 years old and every since then I occasionally have esophageal reflux and choke. Is there any thing that I can use safely? I’m 80 years old.
Hello Lynn,
Thank you for your comment and for sharing your experience. At 80, it’s great that you’re still exploring ways to stay safe and comfortable with your dentures.
For individuals who have a history of choking or esophageal reflux — like yourself — some denture adhesives can pose challenges. If adhesive spreads too far toward the throat or forms stringy residue, it can increase the risk of gagging or make swallowing more difficult.
Here are a few suggestions that may help:
– Use minimal adhesive: Applying a very small amount in strategic spots (not too close to the back edges) can help avoid excess ooze or material shifting toward the throat.
– Try powder adhesive: Some people find that denture adhesive powders (like Super Poligrip Powder) feel lighter and less intrusive than creams, which may be better tolerated if you’re sensitive to bulk or residue near the throat.
– Zinc-free options: Stick with zinc-free adhesives, as they’re safer for long-term use and may cause fewer side effects.
Since you’ve experienced past respiratory issues, it’s best to talk to your dentist about the safest adhesive for you — or whether a different type of denture fit or reline might help avoid the need for adhesive altogether.
You’re not alone in facing this issue, and with a few careful adjustments, there are safe options that may help you feel more secure and comfortable.
Let us know how you go. Thanks again, and all the best.
I’m new at this. Seems there is a problem. If I use too much it comes out and is a horrible horrible mess. How do I clean up the mess after using too much after putting my dentures in?
Hi Debbie,
Thanks for your comment, and welcome to the world of dentures! You’re definitely not alone — many new denture wearers go through the same trial-and-error stage with adhesive.
If you’ve used too much and it’s oozing out, here’s a quick way to clean up the mess:
– Remove excess adhesive from around your mouth using a damp cloth or paper towel. Warm water helps loosen the adhesive if it’s sticky.
– Rinse your mouth with warm salt water or a gentle mouthwash to clear away any residue left on your gums.
– Remove the dentures carefully if needed, and wipe away any extra adhesive from the denture itself using a soft cloth, denture brush, or even a cotton swab.
– Avoid scraping or using anything sharp, as this can damage your dentures.
For next time, try applying just a few small dabs — usually 3 to 4 pea-sized dots for uppers, and 2 to 3 for lowers is plenty. Avoid spreading it too close to the edges.
It might take a few tries to find the right amount for your mouth, but it gets easier! If you’re still having trouble, ask your dentist to check the fit — sometimes adjustments or a soft reline can reduce the need for adhesive altogether.
Feel free to reach out again if you have more questions, and all the best.
Jade
I HAVE USED FIXODENT FOR 7 YEARS. NOW I HAVE MOVED TO A DIFFERENT BRAND THAT IS ZINC FREE. MY ISSUE IS I GET THESE ATTACKS AROUND 4 TIMES A DAY. I GET A CHILL UP MY BODY THEN I GET A FEELING AROUND MY FACE FOR ABOUT 7 SECONDS THEN IT GOES AWAY. MY DOCTORS CAN NOT FIGURE OUT HOW TO GET RID OF THIS, SO I HAVE NO MORE ATTACKS. IS ANYONE ELSE SEEING WHAT I AM SEEING?
Hello Richard,
Thank you for sharing your experience — that sounds very uncomfortable and concerning. I can understand how frustrating it must be not having clear answers yet.
While denture adhesives are generally safe when used correctly, some people can experience reactions to certain ingredients, even in zinc-free products. These reactions might include sensitivity, tingling, or unusual sensations. However, as far as I know, what you’re describing — chills and facial sensations — isn’t a typical side effect of most denture adhesives. But please note that I am not a healthcare professional.
Since you’ve already seen your doctor, it may be worth discussing this again and mentioning the exact brand and ingredients in your new adhesive. Bringing the product packaging to your appointment can help them check for any potential allergic or neurological triggers. You might also ask for a referral to an allergist or neurologist if they haven’t already suggested that.
In the meantime, you might want to consider pausing the new adhesive for a few days (if possible) to see whether the sensations lessen. If they do, that might help pinpoint whether the adhesive is a contributing factor. Just be sure to check with your dentist before making long-term changes.
You’re not alone in this — some denture wearers do experience unusual reactions when switching products. Maybe some other readers have had a similar experience and share their story. I hope you find relief and some clear answers soon.
Hello, I have worn a partial plate for decades and to keep the cost down of replacing a lose plate I use Polident denture cream, the plate itself has become rather lose. I currently have a sore tongue, to look at it its perfectly normal, I am currently suffering from an infected lip from sunburn, antibiotics and antifungal treatment aren’t fixing it. I drove machinery for many years without cabs, cabs themselves weren’t available 50 years ago so we all got roasted but the job had to be done. I have had 2 lower lip biopsies both were negative. My dentist never noticed anything during my recent visit but my lower still burns. How much of this is due to the Polident adhesive cream I’m currently using?
Hi Richy,
Thanks for sharing your experience. It’s difficult to say how much of this may be due to the Polident adhesive cream, especially as there are a few things happening at once.
Denture adhesive can sometimes cause irritation, especially if the plate is loose and you’re needing to use more adhesive than usual to keep it in place. A loose partial can also rub against the tongue, gums, or soft tissue, even if everything looks fairly normal at first glance.
That said, the ongoing burning in your lower lip and the infected sunburn area should definitely be followed up with your dentist, doctor, or an oral medicine specialist, particularly since antibiotics and antifungal treatment haven’t fixed it. It’s good that your biopsies were negative, but persistent burning or soreness is still worth checking further.
You could also ask your dentist whether switching to a zinc-free or different type of adhesive may be worth trying, and whether your partial plate needs relining, adjustment, or replacement.
I hope you get some answers soon, and thanks again for commenting.
Jade