Denture Adhesives Side Effects, Benefits & Common Problems

Last Updated on November 6, 2023 by Jade

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denture adhesives side effects

Denture adhesives are a good solution for denture wearers to hold dentures in place. However, potential issues can develop.

In this article we’ll look at what denture adhesives are, how they work, discuss some denture adhesives side effects, other problems you may experience, and how to fix issues you may have.

What Are Denture Adhesives?

Denture adhesives are used as denture glue to hold dentures firmly in place in your mouth. These adhesives are available in three common formats: as a paste, powder, or pad.

When you use a dental adhesive, you apply it directly to the fitting surface of the full denture plate or the base. When you put the denture in your mouth, the adhesive sits between the plate and your gums.

The adhesive is meant for daily use. So before going to bed each night, it’s important to make sure that you carefully remove the denture adhesive from the denture plates as well as your gums or oral tissues when you clean your dentures.

The Benefits of Denture Adhesive

There are a few basic advantages to using a denture adhesive cream on dentures. They include:

  1. Prevent Your Dentures From Moving: As you age, you might not find your dentures fitting as well as they used to because your gums change shape over time. However, using a denture adhesive ensures the firm positioning of the dentures in your mouth.
  2. Improved Comfort: As for comfort, you have to consider that a denture is a hard material that is going to spend most of the day on the soft tissue of your mouth. The dental adhesive makes that fit a lot more comfortable for the wearer.
  3. Improves Your Self-Confidence: Since your dentures will be firmly held in place, you don’t have to worry about your dentures moving inside your mouth (or falling out) when you are around others when talking and eating. This will help with your self-confidence, especially when in public, immensely.

6 Common Problems With Denture Adhesives

The biggest issue that can result from the use of denture adhesives is what would be classified as side effects. Here are the top six denture adhesive side effects to be aware of:

  1. Bone Loss: Denture wearers are subject to the natural loss of bone density. This happens over time as your jawbone no longer receives the type of stimulation it once experienced with teeth or dental implants in place. As the bone deteriorates, there is less of it to support the denture plates. One thing that can speed up bone loss is the habit of wearing dentures that do not fit properly. Some people may be over-reliant on denture adhesives to keep their dentures in place rather than getting new dentures or a denture reline when their dentures don’t fit properly. This is why it is vital for regular denture fixing or repair to ensure a snug, comfortable fit.
  2. Zinc Toxicity: Zinc is a requirement of the human body but only in small amounts. It is used to assist with proper healing and good immune function. However, if zinc enters the body in larger amounts, it can be toxic causing nerve damage and prolonged numbness. Denture adhesives were loaded with zinc and many manufacturers have created new formulas that are zinc-free and better for denture wearers. Read the labels to ensure you are using a zinc-free denture adhesive product.
  3. Stomach Problems: The complex mixture of chemical compounds used in the ingredients of any denture glue can be dangerous to your digestive system if swallowed. The packaging of these products has warnings listed to this effect. One way to ensure you do not swallow the adhesive product is to apply only enough that extra glue does not ooze out from the sides of your dentures and into your mouth. Once you find the correct amount to apply, you can minimize the possibility of this being an issue.
  4. Allergic Reaction: As mentioned above, the formula used in creating any kind of denture adhesive is a mixture of many different chemical compounds. This is true even with the best denture adhesive on the market. Therefore, it’s possible that there could be an ingredient that may trigger an allergic reaction of some kind. This would make wearing dentures even more difficult if that reaction affected the gums or mouth. Be sure to read the ingredient list before trying a dental glue product.
  5. Bad Taste: Considering that zinc and other chemicals are used in dental glue, it only makes sense that it is not going to taste very good. For some denture wearers, the taste of the denture cream is enough to make them sick to their stomachs. With this kind of reaction, it becomes difficult to use a product that ends up so close to the taste buds. However, over time, many denture wearers can get used to the taste or smell of the products that they no longer react to them.
  6. Denture Movement: Denture adhesives may lose their hold over time, causing the dentures to slip, shift, or move around in the mouth. This can cause discomfort, soreness, or pain.

Denture Adhesives Side Effects FAQs

Are there side effects when using denture adhesives?

Typically, any side effects that develop through the use of denture adhesives are not normally considered harmful. However, it is not uncommon for some individuals to be triggered by ingredients found in denture adhesives. These triggers can result in allergic reactions. Denture adhesives containing acrylic acid or zinc are usually the culprits.

Some people can have serious reactions to acrylic acid in denture adhesives. Symptoms include face or tongue swelling, breathing problems or anaphylaxis. Seek emergency medical attention immediately.

If your denture adhesive contains zinc, then zinc toxicity might result from prolonged use. Be conscious of signs such as arm or leg weakness, body tingles, or numbness.

Contact your dental professional if denture adhesives cause you any side effects.

What should I do if I experience a side effect from my denture adhesive?

There are two key actions to take if you experience side effects from using denture adhesives. First, stop using the product. Second, contact your dental professional.

Side effects may go away as soon as you stop using the dental adhesive. Your dental professional may suggest a change in products that could eliminate the side effects. Or they may suggest adjustments to your dentures to improve how they fit in your mouth. This may mean that you don’t require the use of denture adhesives. Or, if these courses of action don’t help, other treatments may be necessary.

Can using too much denture adhesive cause side effects?

When too much denture adhesive is used, it can leak out from between your gums and dentures. This leaking can cause the adhesive to come into contact with the tissues in your mouth. This may irritate and make your mouth sore or inflamed. Also, when too much denture adhesive used, it can impact how dentures fit. This can cause them to slip out of place.

If there is excess dental adhesive in your mouth, you could swallow some. Ingesting denture adhesive can cause nausea, diarrhea, or vomiting.

If denture adhesives trigger any reaction, consult with your dental professional. They can identify the cause and provide appropriate treatment.

Should I stop using my denture adhesive if I experience side effects?

If your denture adhesive causes a side effect, stop using it immediately. Contact your dental professional for advice. It may require changing denture adhesive products or having adjustments performed on your dentures.

Can denture adhesive side effects be prevented?

Preventing all side effects may not be possible. However, the risk of experiencing issues can be reduced by:

– Following the Instructions: You will find instructions printed on the denture adhesive packaging. Read and follow them.
– Using the Recommended Amount: The instructions will tell you what the recommended amount of denture adhesive should be. Use only this amount to hold your dentures in place.
– Keeping Your Dentures Clean: Before you apply denture adhesive, ensure that the denture is cleaned properly. Failing to do this may cause gum irritation should food particles or bacteria get trapped between gums and dentures.
– Avoiding Use If Gums Are Damaged or Inflamed: If you are experiencing pain in your gums because they are swollen or irritated, refrain from applying denture adhesive. Allow your gums to heal before using denture adhesive again.
– Avoiding Allergens: Read the ingredient list on the packaging. If you’re allergic to any ingredient, don’t use the denture adhesive.

Final Thoughts

While denture adhesives are great to hold dentures in place, they aren’t always the best solution. Your dental professional may advise adjusting your dentures if your dentures are loose fitting.

Using too much can cause your dentures to slip and can result in irritation to your gums. Plus, excess denture adhesive may be swallowed which can cause other health issues. There are ingredients contained in denture adhesives that may result in allergic reactions. To avoid this, read the list of ingredients, and if you have a known allergy to any, change products.

Remember, if you have a reaction from using denture adhesive, stop using it. Seek medical attention if the reaction is serious. Otherwise, consult with your dental professional to determine the possible cause and appropriate treatment.

About Jade Roberts

After having a lot of dental issues when she was younger, and years of restorative dental work, Jade knows how difficult it is to find the right dental information. This forced her to do countless hours of research and connect with dental experts all over the world to find the right information. Learning has made her passionate about sharing her knowledge and experience so that others don't have to go through the same issues. "If I make any recommendations in the articles on the False Teeth Options website, it is because my team and I have researched and/or tested the products ourselves, and would be comfortable recommending them to our own family and friends. I'd love to hear of your experiences. So if you have any questions or comments, please feel free to get in touch."


  1. nadine briggs on June 6, 2022 at 6:14 pm

    I am allergic to Iodine …..Is there Iodine in denture adhesive ?

    • False Teeth Options on June 8, 2022 at 1:53 am

      Hi Nadine, and thanks for your question.
      I am not aware of iodine in denture adhesive. However, you may wish to check out the ingredient list on the packaging, or via the manufacturer’s website.
      Eg. See Fixodent ingredients – click here.

  2. Savinia on August 19, 2023 at 4:03 pm

    By swallowing the teeth adhesive can this cause problems with constipation in a person ?

    • Jade Roberts on August 20, 2023 at 6:30 pm

      Hello Savinia
      I have not experienced issues like this. But please note, I am not a healthcare professional so if you have any specific questions, you may want to see a professional.
      From the research that I have done, swallowing a small amount of denture adhesive is unlikely to cause significant problems with constipation. Denture adhesive is typically formulated to be safe if accidentally ingested in small quantities.
      However, if you have accidentally swallowed teeth adhesive and are experiencing symptoms such as constipation, it’s a good idea to consult a medical professional for guidance. While the adhesive itself might not directly cause constipation, there could be other factors involved that are leading to your symptoms. It’s always best to seek medical advice to ensure your health and well-being.

  3. Stanley Williams on November 14, 2023 at 1:56 pm

    I use a dental adhesive and I am also suffering from dangerous uric acid readings which are causing joint pain and some bleeding gums

    Could this be caused by my dental adhesive.?Uric acid reading are dangerous as I have said over 9 when my understanding is that they should be 5.

    At the moment, the “medical professionals” are treating me with gout medications like Allopurinol, even though I do not have gout.

    • Jade Roberts on November 16, 2023 at 10:29 pm

      Hello Stanley
      Thank you for your question, and I am sorry to hear of the issues you are having.
      Please note that I am not a dentist or health professional, so any comments are from my personal experience or research that I have done.
      Most of the time denture adhesives are pretty safe, but bodies can react differently. If you’re thinking your adhesive might be causing an issue, it’s a good idea to chat with your dentist about it. High uric acid can be a real pain, literally. From what I understand it might lead to gout. That’s something you’d want to manage with a doctor’s help. They can guide you on how to keep it under control. Bleeding gums are a bit of a concern. It could be something like gum disease. It may not be directly linked to the uric acid issue, but it’s still worth mentioning to your dentist.
      With everything going on – the joint pain, high uric acid, and gum issues – it’s really important to have a chat with both your doctor and dentist. They should be able to work together to figure out what’s going on and how to make you feel better.
      Best of luck with it, and let us know how you go.

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